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Articles related to "immune"


Qualified Immunity: Explained

  • Consider this example of how effortlessly courts use qualified immunity to sweep away serious constitutional violations: In April 2013, police officers in Texas responded to a dispatch describing a Black man in a brown shirt, who was firing his gun at mailboxes in a residential neighborhood.
  • Thus, as a result of the Supreme Court’s aggressive defense of qualified immunity, victims of civil rights violations may be less likely to find a lawyer who is willing to represent them and suits will not be brought in the first place.
  • In an opinion filed in March 2019, for instance, the U.S. Court of Appeals for the Ninth Circuit held that officers were immune from liability for the deliberate stealing of property simply because there was no “clearly established” case law governing the circumstances.

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How long does the coronavirus last inside the body?

  • It’s important to understand COVID-19 persistence, as this knowledge determines how long someone is contagious, how long patients should stay in isolation, and even whether it’s possible to be re-infected.
  • One study in Germany looked at nine mild cases and found that live viruses could not be grown from throat swabs or sputum samples eight days after symptoms started.
  • Another study in Nature isolated the live virus from nine COVID-19 patients during their first week of symptoms.
  • Working out the true windows of viral persistence will help resolve whether people are being re-infected with COVID-19, whether they develop lasting immunity—and, ultimately, how long sick people need to stay isolated.
  • Griffin says that even if the virus isn’t spreading profusely, if its proteins are still being produced in a small number of cells, its fragments may force your body to maintain an immune response—keeping you from getting sick again.

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Scientist warns against fast-tracking COVID-19 vaccine trials

  • As efforts to find an effective vaccine for SARS-CoV-2 ramp up, an immunologist warns that fast-tracking of clinical trials could be catastrophic.
  • Phase II trials involve investigating the immune response in a larger cohort.
  • Phase III trials involve much larger groups of people (sometimes in the thousands) and must show, in a statistically significant manner, that the vaccine can protect against infection.
  • The article in Science Advances warns that this route could be dangerous and says scientists must conduct comprehensive safety tests for any potential vaccine.
  • In the failed RSV vaccine, there was a lack of antibody affinity maturation, which caused the children to have a worse response than usual when they contracted the virus.
  • Studies of immune responses to SARS-COV-2 have found that the numbers of CD4+ T cells are crucial for overcoming the disease, which is a vital consideration for vaccine development.

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