The top four teams in the playoff field are LSU, Ohio State, Clemson and Oklahoma, in that order, the selection committee announced Sunday.
In the semifinals, LSU will face Oklahoma at the Chick-fil-A Peach Bowl at Mercedes-Benz Stadium in Atlanta, while Ohio State will take on Clemson at the PlayStation Fiesta Bowl at State Farm Stadium in Glendale, Arizona.
The national championship game is January 13 at the Mercedes-Benz Superdome in New Orleans.
This marks the fifth consecutive appearance in the playoff for Clemson, the defending national champion.
It's LSU's first time in the College Football Playoff.
The College Football Playoff has been around since the 2014 season, replacing the Bowl Championship Series.
The playoff teams are selected by a 13-person committee, which ranks teams based on performance, strength of schedule, conference championships won, head-to-head results and comparing results against common opponents.